10.6084/m9.figshare.10258334.v1
José Artur Brilhante Bezerra
José Artur Brilhante
Bezerra
Ilanna Vanessa Pristo de Medeiros Oliveira
Ilanna Vanessa Pristo de Medeiros
Oliveira
Ana Carolina Yamakawa
Ana Carolina
Yamakawa
Mariana Guimarães Nilsson
Mariana Guimarães
Nilsson
Klívio Loreno Raulino Tomaz
Klívio Loreno Raulino
Tomaz
Kalyne Danielly Silva de Oliveira
Kalyne Danielly Silva de
Oliveira
Célio Souza da Rocha
Célio Souza da
Rocha
Cecília Irene Perez Calabuig
Cecília Irene Perez
Calabuig
Felipe Fornazari
Felipe
Fornazari
Helio Langoni
Helio
Langoni
João Marcelo Azevedo de Paula Antunes
João Marcelo Azevedo de Paula
Antunes
Serological and molecular investigation of Leishmania spp. infection in cats from an area endemic for canine and human leishmaniasis in Northeast Brazil
SciELO journals
2019
Leishmaniasis
Felis catus
zoonosis
epidemiology
IFAT
2019-11-06 02:45:56
Dataset
https://scielo.figshare.com/articles/dataset/Serological_and_molecular_investigation_of_Leishmania_spp_infection_in_cats_from_an_area_endemic_for_canine_and_human_leishmaniasis_in_Northeast_Brazil/10258334
<div><p>Abstract The aim of this study was to investigate the occurrence of Leishmania spp. antibodies, and its association with feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV), in domestic cats from an area endemic for canine and human leishmaniasis in Rio Grande do Norte State, Brazil. Ninety-one cats were subjected to a complete clinical exam, and blood samples were collected. An epidemiological questionnaire was used to investigate the risk factors. IgG anti-Leishmania spp. antibodies were detected by immunofluorescence antibody test (IFAT), with a cut-off value of 1:40. Polymerase chain reaction (PCR) was performed to detect genetic material of Leishmania spp. in the blood samples. The presence of antibodies against FIV and antigens of FeLV was evaluated using an immunochromatographic test. Seropositivity for Leishmania spp., FIV, and FeLV was observed in 14/91 (15.38%), 26/91 (28.57%), and 3/91 (3.29%) cats, respectively. All samples gave negative results on PCR analysis. Based on these data, no significant statistical association was observed between seropositivity for Leishmania spp., and sex, age, presence of clinical signs, evaluated risk factors, and positivity for retroviruses. These findings demonstrated for the first time that cats from Mossoró, Rio Grande do Norte, are being exposed to this zoonosis and might be part of the epidemiological chain of transmission of visceral leishmaniasis.</p></div>