10.6084/m9.figshare.5666392.v1
Eduardo Louzada da Costa
Eduardo Louzada da
Costa
Luiz Eduardo Moreira Teixeira
Luiz Eduardo Moreira
Teixeira
Bruno Jannotti Pádua
Bruno Jannotti
Pádua
Ivana Duval de Araújo
Ivana Duval de
Araújo
Leonardo de Souza Vasconcellos
Leonardo de Souza
Vasconcellos
Luide Scalioni Borges Dias
Luide Scalioni Borges
Dias
Biomechanical study of the effect of platelet rich plasma on the treatment of medial collateral ligament lesion in rabbits
SciELO journals
2017
Medial Collateral Ligament, Knee
Knee Injuries
Rabbits
2017-12-05 08:39:24
Dataset
https://scielo.figshare.com/articles/dataset/Biomechanical_study_of_the_effect_of_platelet_rich_plasma_on_the_treatment_of_medial_collateral_ligament_lesion_in_rabbits/5666392
<div><p>Abstract Purpose: To evaluate the use of platelet-rich plasma in the early stages of healing of traumatic injury of the medial collateral ligament in the knee of rabbits. Methods: Thirty rabbits were subjected to surgical lesion of the medial collateral ligament. Of these, 16 were treated with platelet-rich plasma and 14 with saline (control). After 3 and 6 weeks of treatment, 50% of the animals from each group were sacrificed, and biomechanical tests were performed on the injured ligament to compare the tensile strength between the two groups. Results: Platelet-rich plasma significantly increased the tensile strength of the ligament in the groups treated after3 and 6 weeks. In the group treated with platelet-rich plasma vs. saline, the tensile strength values were 3192.5 ± 189.7 g/f vs. 2851.1 ± 193.1 g/f at3 weeks (p = 0.005) and 5915.6 ± 832.0 g/f vs. 4187.6 ± 512.9 g/f at 6 weeks (p = 0.0001). Conclusion: The use of platelet-rich plasma at the injury site accelerated ligament healing in an animal model, demonstrated by an increase in the tensile strength of the medial collateral ligament.</p></div>