10.6084/m9.figshare.5720029.v1
Jamil Alli Murad Junior
Jamil Alli
Murad Junior
Maurício Nassau Machado
Maurício Nassau
Machado
Marcio Pimentel Fernandes
Marcio Pimentel
Fernandes
Marcelo José Ferreira Soares
Marcelo José Ferreira
Soares
Ingrid Helen Grigolo
Ingrid Helen
Grigolo
Cristiane Carvalho Singulane
Cristiane Carvalho
Singulane
Moacir Fernandes de Godoy
Moacir Fernandes de
Godoy
B-Type Natriuretic Peptide as a Predictor of Short-Term Mortality in On-Pump Coronary Artery Bypass Grafting
SciELO journals
2017
Natriuretic Peptides
Coronary Artery Bypass
Prospective Studies
2017-12-20 02:58:56
Dataset
https://scielo.figshare.com/articles/dataset/B-Type_Natriuretic_Peptide_as_a_Predictor_of_Short-Term_Mortality_in_On-Pump_Coronary_Artery_Bypass_Grafting/5720029
<div><p>Abstract Objective: The present study refers to a determination of the preoperative B-type natriuretic peptide is a predictor of short-term all-cause mortality in patients undergoing on-pump coronary artery bypass graft surgeries. Methods: Two hundred and twenty-one patients undergoing on-pump coronary artery bypass graft surgeries were evaluated prospectively during a 30-day postoperative follow-up period. Serum B-type natriuretic peptide concentration was measured without a 24-hour period prior to the surgical procedure and the value obtained was correlated with a short-term all-cause mortality. Results: Data analysis showed that all-cause mortality rates were equal to 9.5% in 30 days. Accuracy analysis by the receiver operating characteristic curve found an ideal cut-off value of B-type natriuretic peptide equal to 150 pg/mL in relation to mortality (AUC=0.82, 95% CI=0.71-0.87, P<0.001). Multivariate analysis showed that B-type natriuretic peptide value greater than or equal to 150 pg/mL (P=0.030, HR=3.99, 95% CI=1.14-13.98) was an independent predictor of all-cause mortality in a 30-day follow-up period. Conclusion: Preoperative serum B-type natriuretic peptide concentration is an independent predictor of short-term all-cause mortality in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass.</p></div>