Gomes, V. Baldacim, V.A.P. Costa, J.F.R. Silva, C.P. Costa e Arcaro, J.R.P. Miranda, M.S. Sousa, R.S. Fagliari, J.J. Madureira, K.M. Cellular immunity in Holstein cows seropositive for Bovine Leukosis Virus (BLV) during the transition period <p></p><p>ABSTRACT This research evaluated the dynamics of leukocytes and lymphocytes subsets in seropositive Holstein cows for BLV during the transition period. Blood samples (n=72) from 12 cows were harvested from week -2 up to week +3 to perform leukogram, immunophenotyping, cortisol and haptoglobin (Hp). Leukocytes pattern was characterized by leukocytosis, neutrophilia, monocytosis and eosinopenia around calving. Lymphocytosis and high proportions of B cells CD21+ were a constant finding between week -2 and +3, thus cows were tested and confirmed seropositive for BLV. The values of T lymphocytes subsets were low during the transition period, observing two peaks that coincided with high levels of cortisol at delivery (2.11µg/dL) and week +3 (1.97µg/dL). Hp had gradual increase from week -2 (166µg/mL) until week +3 (576g/mL) probably due to high rate of uterine infection detected between week +2 and +3. The seropositive cows for BLV presented stress leukogram around delivery, except for lymphocytes. Lymphocytosis and the high proportions of B cells, associated with the low proportions of T lymphocytes, can be indicative of immunosuppression and predisposition to the inflammatory process observed in the post-partum period.</p><p></p> peripartum;haptoglobin;cortisol;lymphocytes subsets 2018-01-17
    https://scielo.figshare.com/articles/dataset/Cellular_immunity_in_Holstein_cows_seropositive_for_Bovine_Leukosis_Virus_BLV_during_the_transition_period/5792064
10.6084/m9.figshare.5792064.v1