10.6084/m9.figshare.5792175.v1 Rogevando Rodrigues Nunes Rogevando Rodrigues Nunes Paulo Giordano Baima Colares Paulo Giordano Baima Colares Juliana Pinto Montenegro Juliana Pinto Montenegro Is Pethidine Safe during Labor? Systematic Review SciELO journals 2018 pethidine safety labor 2018-01-17 02:46:56 Dataset https://scielo.figshare.com/articles/dataset/Is_Pethidine_Safe_during_Labor_Systematic_Review/5792175 <div><p>Abstract Purpose To verify if pethidine is safe for the conceptus when used during labor. Methods Systematic review in the Capes Periodicals/PubMed and MEDLINE/Virtual Health Library (BVS, in the Portuguese acronym) databases. Results A total of 17 studies published from January 1st, 2000, to September 2nd, 2016, with a total of 1,688 participants involved were included in the present review. There was no record of conceptus vitality decrease associated with low doses of pethidine being administered to mothers during labor. Conclusions Intramuscular (IM) or intravenous (IV) pethidine at low doses, of up to 50 mg, is safe to administer during labor.</p></div>