%0 Generic %A Santos, Francilayne Moretto dos %A Peres, Aline Krampe %A Mandotti, Michel Roberto %A Peres, Luis Alberto Batista %D 2018 %T Metabolic investigation in patients with nephrolithiasis %U https://scielo.figshare.com/articles/dataset/Metabolic_investigation_in_patients_with_nephrolithiasis/5816271 %R 10.6084/m9.figshare.5816271.v1 %2 https://scielo.figshare.com/ndownloader/files/10285503 %2 https://scielo.figshare.com/ndownloader/files/10285512 %K Nephrolithiasis/metabolism %K Hypercalciuria %K Uric acid %X

ABSTRACT: Objective: To evaluate the prevalence of metabolic disorders associated with nephrolithiasis in a female population. Methods: A retrospective study on 1,737 patients with evidence of recent formation of renal stones, being 54% females. The laboratory investigation consisted of at least two samples of blood and 24-hour urine to assess calcium, uric acid, citrate and creatinine levels, qualitative cystinuria, urinary pH following fasting and 12-hour water restriction, urine culture, serum creatinine and parathyroid hormone. Results: The most frequent alterations were hypercalciuria (40.9%), urinary tract infection (23.2%), hypocitraturia (22.4%), low urinary volume (20.5%) and hyperuricosuria (16%). Conclusion: The most frequent metabolic alterations in females were hypocitraturia, urinary tract infection, low urinary volume and hyperuricosuria.

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