Effect of essential oils from Mangifera indica L. cultivars on the antifungal susceptibility of Candida spp. strains isolated from dogs Raquel Oliveira dos Santos FONTENELLE Antonio Carlos Nogueira SOBRINHO Bruna Vieira SOARES Francisca Lidiane Linhares de AGUIAR Erika Helena Sales de BRITO Carolina Sidrim de Paula CAVALCANTE Marcos Fábio Gadelha ROCHA Selene Maia de MORAIS 10.6084/m9.figshare.5861880.v1 https://scielo.figshare.com/articles/dataset/Effect_of_essential_oils_from_Mangifera_indica_L_cultivars_on_the_antifungal_susceptibility_of_Candida_spp_strains_isolated_from_dogs/5861880 <div><p>SUMMARY This work reports the chemical study, and anti-Candida spp. activity of leaf essential oil from Mangifera indica cultivars. The essential oils were obtained by hydro-distillation and analyzed by gas chromatography/mass spectroscopy. The anti-Candida spp. activity was evaluated against strains isolated from dogs by the agar-well diffusion method and the minimum inhibitory concentration (MIC) by the broth microdilution method. Tommy Atkins cultivar presented β–selinene (29.49%), caryophyllene oxide (12.40%) and humulene II epoxide (8.66%) as main constituents, while the main constituents of Rosa, Moscatel and Jasmim varieties were caryophyllene oxide (23.62, 48.42 and 30.77%, respectively) and humulene epoxide II (11.56, 23.45, and16.27%, respectively). The means of inhibition zones were 11 ± 0.71, 13.5 ± 3.54, 10.5 ± 0.71 and 13.5 ± 0.71mm to Tommy Atkins, Rosa, Moscatel and Jasmim varieties, respectively. For Tommy Atkins, the MIC ranged from 0.62 to 1.25 mg/mL; for Rosa, ranged from 0.31 to 1.25 mg/mL; for Jasmim ranged from 0.31 to 0.62 mg/mL; while for the Moscatel variety the MIC value was 1.25 mg/mL for all Candida strains. Essential oils of four M. indica cultivars were active in vitro against Candida spp., demonstrating good antifungal activity and can be a useful source of antifungal compounds for veterinary medicine.</p></div> 2018-02-07 02:51:15 mango yeasts aromatic oils caryophyllene oxide small carnivores