Effect of essential oils from Mangifera indica L. cultivars on the antifungal susceptibility of Candida spp. strains isolated from dogs
Raquel Oliveira dos Santos FONTENELLE
Antonio Carlos Nogueira SOBRINHO
Bruna Vieira SOARES
Francisca Lidiane Linhares de AGUIAR
Erika Helena Sales de BRITO
Carolina Sidrim de Paula CAVALCANTE
Marcos Fábio Gadelha ROCHA
Selene Maia de MORAIS
10.6084/m9.figshare.5861880.v1
https://scielo.figshare.com/articles/dataset/Effect_of_essential_oils_from_Mangifera_indica_L_cultivars_on_the_antifungal_susceptibility_of_Candida_spp_strains_isolated_from_dogs/5861880
<div><p>SUMMARY This work reports the chemical study, and anti-Candida spp. activity of leaf essential oil from Mangifera indica cultivars. The essential oils were obtained by hydro-distillation and analyzed by gas chromatography/mass spectroscopy. The anti-Candida spp. activity was evaluated against strains isolated from dogs by the agar-well diffusion method and the minimum inhibitory concentration (MIC) by the broth microdilution method. Tommy Atkins cultivar presented β–selinene (29.49%), caryophyllene oxide (12.40%) and humulene II epoxide (8.66%) as main constituents, while the main constituents of Rosa, Moscatel and Jasmim varieties were caryophyllene oxide (23.62, 48.42 and 30.77%, respectively) and humulene epoxide II (11.56, 23.45, and16.27%, respectively). The means of inhibition zones were 11 ± 0.71, 13.5 ± 3.54, 10.5 ± 0.71 and 13.5 ± 0.71mm to Tommy Atkins, Rosa, Moscatel and Jasmim varieties, respectively. For Tommy Atkins, the MIC ranged from 0.62 to 1.25 mg/mL; for Rosa, ranged from 0.31 to 1.25 mg/mL; for Jasmim ranged from 0.31 to 0.62 mg/mL; while for the Moscatel variety the MIC value was 1.25 mg/mL for all Candida strains. Essential oils of four M. indica cultivars were active in vitro against Candida spp., demonstrating good antifungal activity and can be a useful source of antifungal compounds for veterinary medicine.</p></div>
2018-02-07 02:51:15
mango
yeasts
aromatic oils
caryophyllene oxide
small carnivores