10.6084/m9.figshare.7243580.v1 Rodrigo Gomes de Oliveira Rodrigo Gomes de Oliveira Domingos de Morais Filho Domingos de Morais Filho Carlos Alberto Engelhorn Carlos Alberto Engelhorn Iruena Moraes Kessler Iruena Moraes Kessler Felipe Coelho Neto Felipe Coelho Neto Foam sclerotherapy for lower-limb varicose veins: impact on saphenous vein diameter SciELO journals 2018 Ultrasonography Varicose veins Sclerotherapy Saphenous vein Venous insufficiency 2018-10-24 02:41:25 Dataset https://scielo.figshare.com/articles/dataset/Foam_sclerotherapy_for_lower-limb_varicose_veins_impact_on_saphenous_vein_diameter/7243580 <div><p>Abstract Objective: To assess changes in the great saphenous vein (GSV) after foam sclerotherapy for varicose veins. Materials and Methods: This was a prospective study of 33 patients who were treated with polidocanol foam sclerotherapy after having had varicose veins with a clinical severity-etiology-anatomy-pathophysiology classification of C4-C6 for three months. The patients were evaluated by ultrasound before, during, and after the procedure (on post-procedure days 7, 15, 30, 60, and 90). The GSV diameter, the rate of venous occlusion, and the rate of reflux elimination were determined. Two patients were excluded for having a history of deep vein thrombosis history, and one was excluded for having bronchial asthma. Results: Thirty patients (26 females and 4 males, with mean age of 62 years) completed the protocol. The mean pre-procedure GSV diameter was 6.0 ± 0.32 mm (range, 3.6-11.2 mm). During the sclerotherapy, the mean GSV diameter was reduced to 1.9 ± 0.15 mm (range, 0.6-3.8 mm). On post-procedure day 7, the mean GSV diameter increased to 6.3 ± 0.28 mm (range, 3.9-9.7 mm). On post-procedure day 90, the mean GSV diameter was 4.0 ± 0.22 mm (range, 1.9-8.2 mm). The rate of GSV reflux was significantly lower in the assessment performed on post-procedure day 90 than in the pre-procedure assessment (p < 0.0028). Conclusion: On the basis of our ultrasound analysis, we can conclude that foam sclerotherapy for varicose veins results in a significant reduction in GSV diameter, as well as in the elimination of GSV reflux.</p></div>