%0 Generic %A Ozal, Sadık Altan %A Kupelı, Ayca %A Ozal, Ece %A Gurlu, Vuslat %D 2019 %T Optical biometry-based axial length alterations after intravitreal dexamethasone implant %U https://scielo.figshare.com/articles/dataset/Optical_biometry-based_axial_length_alterations_after_intravitreal_dexamethasone_implant/7773431 %R 10.6084/m9.figshare.7773431.v1 %2 https://scielo.figshare.com/ndownloader/files/14473079 %2 https://scielo.figshare.com/ndownloader/files/14473082 %K Axial length, eye %K Dexamethasone/administration & dosage %K Intravitreal injections, Drug implants %K Macular edema %X

ABSTRACT Purpose: To investigate changes in axial length after intravitreal dexamethasone implantation in patients with macular edema. Methods: We performed a prospective comparative study of 46 patients with unilateral macular edema, due to diabetic retinopathy, retinal vein occlusion, and non-infectious uveitis, who underwent dexamethasone implantation. The fellow eyes of the patients were considered the control group. The central macular thickness was measured by spectral-domain optical coherence tomography, and axial length was measured by IOLMaster 700 optical coherence biometry. We compared axial length and central macular thickness values within the groups. Results: In the study group, the baseline central macular thickness was 460.19 ± 128.64 mm, significantly decreasing to 324.00 ± 79.84 mm after dexamethasone implantation (p=0.000). No significant change in central macular thickness measurements was seen in the control group (p=0.244). In the study group, the baseline axial length was 23.16 ± 0.68 mm, significantly increasing to 23.22 ± 0.65 mm after dexamethasone implantation (p=0.039). However, the control group exhibited no significant change in axial length (p=0.123). Conclusions: In addition to significantly reducing central macular thickness measurements, intravitreal dexamethasone implantation also significantly changes optical biometry-based axial length measurements.

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