10.6084/m9.figshare.7865993.v1
Gabriel Pacífico Seabra Nunes
Gabriel Pacífico Seabra
Nunes
Patrícia da Silva Cunha
Patrícia da Silva
Cunha
Daniele Patrícia Dal Bosco
Daniele Patrícia Dal
Bosco
Sandra Lúcia Euzébio Ribeiro
Sandra Lúcia Euzébio
Ribeiro
Challenging Management of Hepatitis B infection in Ankylosing Spondylitis Patients in an Endemic Area during Immunosuppressive Therapy
SciELO journals
2019
Hepatitis
Reactivation
Immunosuppressive therapy
Ankylosing spondylitis
2019-03-20 02:48:40
Figure
https://scielo.figshare.com/articles/figure/Challenging_Management_of_Hepatitis_B_infection_in_Ankylosing_Spondylitis_Patients_in_an_Endemic_Area_during_Immunosuppressive_Therapy/7865993
<div><p>Abstract Hepatitis B infection is a global health issue. When considering patients with rheumatic diseases, this is no different. By using immunosuppressant drugs, such as DMARDs and biologics, viral reactivation is possible, leading to serious consequences on the patient. We report 3 cases of association between ankylosing spondylitis and hepatitis B with the use of immunosuppressant drugs. Case 1 was a patient with previous HBV infection using DMARD. Cases 2 and 3 were patients chronically infected by HBV during immunosuppressant therapy. The management of HBV infection during immunosuppressant therapy is challenging and needs multidisciplinary support.</p></div>