%0 Generic %A Cai, H. %A Shen, H. %D 2019 %T Random-start controlled ovarian stimulation for emergency fertility preservation in a patient with myelodysplastic syndrome: a case report %U https://scielo.figshare.com/articles/dataset/Random-start_controlled_ovarian_stimulation_for_emergency_fertility_preservation_in_a_patient_with_myelodysplastic_syndrome_a_case_report/7942001 %R 10.6084/m9.figshare.7942001.v1 %2 https://scielo.figshare.com/ndownloader/files/14784773 %2 https://scielo.figshare.com/ndownloader/files/14784779 %K Emergency fertility preservation %K Random-start %K Ovarian stimulation %K Myelodysplastic syndrome %X

This study reports a case of a gonadotropin-releasing hormone agonist trigger in a young female with myelodysplastic syndrome (MDS) who underwent fertility preservation using random-start controlled ovarian stimulation. This method involves the stimulation of the ovary regardless of a patient's menstrual-cycle phase. A review of the related literature is also provided. A 17-year-old patient was diagnosed with MDS and required initiation of peripheral blood stem cell transplantation within a maximum of 3 weeks and was in the luteal phase of the menstrual cycle when the possibility of attempting preservation of fertility was presented to her. She opted for a random-start controlled ovarian stimulation with gonadotropins. With successful hemorrhagic prophylaxis, 17 oocytes were retrieved including 10 mature and 7 immature oocytes. Of the immature oocytes, 3 were successfully matured in vitro and a vitrification protocol was used to freeze the 13 mature oocytes.

%I SciELO journals