10.6084/m9.figshare.8127662.v1 Rui Pedro Caetano M. Oliveira Rui Pedro Caetano M. Oliveira Edgar Miguel C. L. T Silva Edgar Miguel C. L. T Silva Carol dos Anjos Marinho Carol dos Anjos Marinho José Ignacio Lopez José Ignacio Lopez Lígia Romana O. A. P. Castro Lígia Romana O. A. P. Castro Solitary fibrous tumor of the kidney: a report of two cases SciELO journals 2019 solitary fibrous tumors kidney neoplasms immunohistochemistry 2019-05-15 02:42:27 Dataset https://scielo.figshare.com/articles/dataset/Solitary_fibrous_tumor_of_the_kidney_a_report_of_two_cases/8127662 <div><p>ABSTRACT Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm, composed of monotonous spindle cells, intermingled with collagen fibers. Kidney location is sporadic, with few reports in literature. We present two cases of 40- and 48-year-old males, one with incidental detection of a peripheral mass; another with hilar lesion perceived following investigation of hematuria. Both revealed a spindle-cell proliferation, without mitosis and necrosis. Immunohistochemical studies: positivity for CD34, CD99 and B-cell lymphoma 2 (Bcl-2). No sign of disease were evident nine and five months after surgery, respectively. SFT is mostly benign, but can show malignant behavior. Morphologic and immunohistochemical characteristics are essential for diagnosis.</p></div>