10.6084/m9.figshare.8163041.v1
Suely Alves Silva
Suely Alves
Silva
Ricardo Emílio Ferreira Quevedo Nogueira
Ricardo Emílio Ferreira Quevedo
Nogueira
Joelane Maria de Carvalho Teixeira
Joelane Maria de Carvalho
Teixeira
José Sílvio Veras Albuquerque
José Sílvio Veras
Albuquerque
Eden Batista Duarte
Eden Batista
Duarte
In vitro cytotoxicity of β-tricalcium phosphate nanoparticles synthesized via solid state reaction
SciELO journals
2019
Biomaterials
β-Tricalcium Phosphate
Cytotoxicity
2019-05-22 02:52:01
Dataset
https://scielo.figshare.com/articles/dataset/In_vitro_cytotoxicity_of_-tricalcium_phosphate_nanoparticles_synthesized_via_solid_state_reaction/8163041
<p></p><p>ABSTRACT The β-tricalcium phosphate (β-TCP) is a synthetic material that present similar chemical composition to bone tissue and is frequently used as biomaterial. In this research, β-TCP was synthesized by solid state reaction and characterized by X-ray Diffraction (XRD), Infrared (IR) Spectroscopy, Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray Spectroscopy (EDX). The surface area and particle size distribution were determined by BET method (Brunauer-Emmet-Teller). A cytotoxicity test was performed according to ISO 10993-5 and ISO 10993-12. Diffraction patterns (XRD) and characteristic functional groups (IR) of material allowed to confirm the formation of the β-TCP phase. BET leaded to verification of the nanometric character of the synthesized particles. SEM allowed to compare the evolution of the microstructural morphology before and after heat treatment. Molar ratio of calcium phosphate nanoparticles, usually used to identify the different phases of apatites, was calculated by EDX. In the cytotoxicity assay, the samples showed no cellular morphological</p><p></p>