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Composition, antioxidant properties, and biological activities of the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez.

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posted on 2019-12-25, 03:00 authored by Natasha Tiemi Fabri, Larissa Junqueira Gatto, Alethéia Santos Furusho, Meira Janette Ballestros Garcia, Francisco de Assis Marques, Marilis Dallarmi Miguel, Deise Prehs Montrucchio, Sandra Maria Warumby Zanin, Obdulio Gomes Miguel, Josiane de Fátima Gaspari Dias

The article has aimed to characterize the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. leaves, in terms of its chemical composition and antioxidant, hemolytic, and phytotoxic potentials, as well as its toxicity against Artemia salina. The major constituents identified by CG-MS were d-elemene, spathulenol, and b-atlantol. When screened for potential biological activities, the essential oil presented low toxicity against Artemia salina, and a capacity of lysing red blood cells. Also, the evaluation of its in vitro antioxidant activity, using the phosphomolybdenum method, showed better results when compared to butylhydroxytoluene (BHT) and rutin. In conclusion, the results obtained showed certain in vitro toxicity, leading to an interesting target for cytotoxicity evaluations of carcinoma cells.

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    Brazilian Journal of Pharmaceutical Sciences

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