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Cytotoxicity and antioxidant activity of goldenberry extracts obtained with high intensity ultrasound

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posted on 2018-02-14, 02:42 authored by Cristiane Franco Codevilla, Bruna Tischer, Amanda Leitão Gindri, Daniele Rubert Nogueira-Librelotto, Juliano Smanioto Barin, Cristiane de Bona da Silva, Clarice Madalena Bueno Rolim, Leila Queiroz Zepka, Cristiano Ragagnin de Menezes

ABSTRACT: The high intensity ultrasound-assisted extraction (HIU) is one of the most simple, quick and efficient techniques for the extraction of phenolic and other antioxidant compounds from plants. This is the first application of HIU for the extraction of these compounds from goldenberry fruit. The HIU and conventional extraction techniques showed similar results regarding to phenolic compounds and antioxidant capacity. However, the time required for HIU extraction (5min) was 24 times lower than conventional extraction (120min). Phenolic compounds reported were chlorogenic acid, caffeic acid and rutin. In vitro cytotoxicity assays were used for evaluation of extracts and the results showed that in a wide range of concentration, the extract maintains cell viability, thus indicating the possibility to use it as food with safety.

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