Fat mass is negatively associated with the physiological ability of tissue to consume oxygen

posted on 28.11.2018 by Valentine Z. Vargas, Claudio A. B. de Lira, Rodrigo L. Vancini, Angeles B. R. Rayes, Marilia S. Andrade

Abstract Aims: To describe the relationship between variables related to body composition and peak oxygen uptake ( V ˙ O 2peak) and to verify whether fat mass can affect these relationships. Methods: Eighty participants underwent cardiopulmonary exercise testing to measure V ˙ O 2peak and a body composition assessment to measure fat mass, fat free mass (FFM), and total body mass (BM). Results: There were significant relationships between V ˙ O 2peak relative to FFM (fat free mass) (mL/kgFFM/min) and absolute fat mass (kg) (r=-0.50, p<0.001) and relative fat mass (%) (r=-0.56, p<0.001). Absolute V ˙ O 2peak (L/min) had a high positive relationship with FFM (r=0.83, p<0.0001); the relationship between V ˙ O 2peak (L/min) and FFM remained high and positive even when accounting for absolute fat mass (kg) (r=0.83, p<0.001). V ˙ O 2peak relative to total body mass (mL/kgBM/min) showed a high negative relationship with relative fat mass (%) (r=-0.89, p<0.001) and a positive relationship with fat free mass (kg) (r=0.57, p<0.001), which did not change when accounting for fat mass (kg) (r=0.56, p<0.001). Conclusion: These data indicate that the physiological ability of tissue to consume oxygen ( V ˙ O 2peak in mL/kgFFM/min) is negatively associated with fat mass. Moreover, the individual’s cardiorespiratory capacity to transport oxygen for working muscles ( V ˙ O 2peak in L/min) is strongly related to absolute FFM, and this association is not affected by fat mass. Finally, a better body mass composition (high FFM and low fat mass) is important for aerobic physical fitness ( V ˙ O 2peak in mL/kgBM/min) and improved physiological ability of tissue to consume oxygen ( V ˙ O 2peak in mL/kgFFM/min).