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\ p None B a = c @ = Z ?N*8 X" 1 Arial1 Arial1 Arial1 Arial1 Arial1 Arial1 Arial General ` Table_1 = $ " Cytokine and growth factors Type Secretion Receptor Function T G F - I
Epithelium FibroblastsB Secreted by proliferative healthy cells. Induces epithelial growth (related to EGF IL-1J Secreted in stress or apoptosis. Stimulates secretion of type II cytokines PDGFr A l o n g T G F s t i m u l a t e t h e p r o l i f e r a t i o n o f f i b r o b l a s t s a n d i n d u c e s e x t r a c e l l u l a r m a t r i x s y n t h e s i s p r o m o t i n g h e a l i n g IGF-I II Epithelium and fibroblasts9 Promotes migration and production of extracellular matrix T G F - 3 Promotes differentiation and inhibits proliferation LIF Inhibits differentiation bFGF Promotes fibroblasts growth KGF III Increases stem cells division HGF Production and migration of TACs M-CSF IV Immune or inflammatory cells$ Promotes the macrophages recruitment IL-87 Positively regulated by M-CSF in inflammatory processes
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