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\ p None B a = c @ = Z ?N*8 X" 1 Arial1 Arial1 Arial1 Arial1 Arial1 Arial1 Arial General ` Table_4 ]$ ! Exams When to collect Therapeutic target Considerations ACT% Immediately after cannulation of ECMO Initially, between 180 and 220 seconds. After collection of test, anticoagulation adjustment should be guided by aPTT or anti-Xa activity. Easy to perform, can be performed at the bedside
Result available quickly
It allows the initial adjustment of heparin infusion aPTTi Daily. It can be collected more than once per day, especially in cases of adjustment of heparin infusion. Keep between 40 and 55 seconds Adequate management of anticoagulation is essential to avoid complications such as system coagulation and intracranial hemorrhage. Anti-Xa activity{ Alternative to the aPTT. It can be collected more than once per day, especially in cases of adjustment of heparin infusion. Keep between 0.2 and 0.3IU/mm PlateletsS Daily. It can be collected more than once per day, especially in cases of bleeding.: Ideally kept greater than 100,000 cells per mm3f Platelets are an essential component of hemostasis and in the prevention of hemorrhagic complications.
Hemoglobin" Ideally kept greater than 8.0 g/dL2 Hemoglobin is a key component of oxygen transport. D-Dimer1 Daily. It can be collected more than once per day Not applicabler Sudden elevation of D-dimer level is strongly indicative of clot formation, predicting failure of the ECMO system. SvcO2 Daily; Ideally maintained greater than 70%, especially in VA-ECMO.- It allows for the adjustment of VA-ECMO flow. PaCO2B Ideally, it was maintained close to 40mmHg, especially in VV-ECMO. Allows for the adjustment of the fresh gas flow rate
Patients with PaCO2 > 50mmHg should be subjected to slow and gradual reduction (not to exceed reduction values greater than 10mmHg per hour).
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